The 10 Best Bed Bug Sprays
We spent 25 hours on research, videography, and editing, to review the top choices for this wiki. Night-night, sleep tight, and don't let the bed bugs bite. But if they do, one of these sprays will take care of the pesky critters in no time. They come in chemical and all-natural varieties, and are also available in travel sizes, so you can keep your hotel room safe when on the go. We've included many options safe for use around pets and kids, too. When users buy our independently chosen editorial picks, we may earn commissions to support our work. Skip to the best bed bug spray on Amazon.
10. Killer Green b52
For sensitive individuals, Killer Green b52 is a great choice, as it has a nice light scent and is non-irritating to the eyes. A little bit goes a long way, and it can even be used on clothes, but it probably isn't strong enough for major infestations.
- dries within minutes
- uses biodegradable salts and enzymes
- may not kill all bugs instantly
|Rating||4.0 / 5.0|
9. Bed Bug Patrol
Bed Bug Patrol is chemical-free so you can feel safe using it around your children or pets. It comes with an in-depth 22-page e-book that gives tips on preventing infestations before they happen and on how best to eliminate them if they do.
- made from plant extracts
- affordable price for a two-pack
- must be applied directly to bugs
|Brand||Bed Bug Patrol|
|Rating||3.8 / 5.0|
8. Eco Raider
Eco Raider is one of the only all-natural products shown to eliminate 100-percent of bed bugs from one exposure. It is a good choice for use in public housing environments or hotels, where an infestation can be a severe issue.
- more effective than pesticides
- keeps killing for weeks afterwards
- smell is overwhelming
|Rating||4.0 / 5.0|
7. Rest Easy
Rest Easy is a must-have for peace of mind when you travel outside your home. It comes in a twin pack of 2 oz. bottles that are compact enough to fit nicely in any bag or purse, and it works like a charm, while leaving behind a pleasing cinnamon scent.
- made from all-natural ingredients
- also kills bed mites
- difficult to apply to large areas
|Rating||3.5 / 5.0|
6. Hot Shot
Hot Shot is an affordable aerosol spray that blankets an area with a fine mist of bed bug killing liquid. It can be used on everything from luggage to baseboards to mattresses, so you can attack every area they might be hiding with one single product.
- gets into hard-to-reach spots
- contains egg killing ingredients
- cannot be used around pets
|Rating||4.1 / 5.0|
5. EucoClean 3-in-1
EucoClean 3-in-1 is ideal for the home, office or a hotel room, as it also works as an all-natural air purifier because of the use of eucalyptus essential oil. It's a great way to be proactive and prevent an infestation before it happens.
- also works on fleas and cockroaches
- works as a natural disinfectant
- has a nice piney smell
|Rating||3.7 / 5.0|
4. Pest Peeve Bye-Bye
Eliminate bed bugs in an environmentally friendly way with the highly-rated Pest Peeve Bye-Bye. It is formulated with a blend of geranium and cedarwood oils, making it safe to use around kids and pets, and can be applied directly to all types of bedding.
- sprays a lot with each squeeze
- made in the usa
- smell is very unpleasant
|Rating||4.4 / 5.0|
3. Harris Egg Kill and Resistant
Depending on the size of your infestation and infested area, you can purchase Harris Egg Kill and Resistant in a 32-oz. or one-gallon bottle. It kills bed bugs almost instantly, and though odorless, it should be used in a well-ventilated area.
- very simple to apply
- can be used on furniture
- approved by the epa
|Rating||4.3 / 5.0|
2. Bedlam Plus
Bedlam Plus was specially designed to get rid of pyrethroid-resistant bed bugs. It uses a combination of quick killing and residual control pesticides to kill not just the bugs, but also their eggs for as long as two weeks after the initial treatment.
- doesn't stain fabrics
- safe for use on wood
- gets into cracks and crevices
|Rating||4.9 / 5.0|
1. Eco Defense
Kill bed bugs on contact with the powerful Eco Defense. It uses a proprietary blend of all-natural, organic ingredients that work to get rid of adults, eggs, and nymphs before they create a colony, and it doesn't stain, so you can apply it directly to linens and bedding.
- used by pest control professionals
- 100 percent child- and pet-safe
- 60-day money-back guarantee
|Rating||5.0 / 5.0|