The 10 Best Pet Stain Removers

Updated May 26, 2018 by Taber Koeghan

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We spent 42 hours on research, videography, and editing, to review the top picks for this wiki. Having a furry friend is among the most enjoyable experiences imaginable, except for the occasional accidents. But as long as you have one of these pet stain removers on hand, there's no reason to let unsightly marks and unpleasant urine odors ruin your carpets and upholstery. When users buy our independently chosen editorial picks, we may earn commissions to support our work. Skip to the best pet stain remover on Amazon.

10. Simple Green

Whether the stain is old and set-in or newly-formed, Simple Green is crafted to remove it completely. It's proven to clean organic materials and odors effectively, without any possibility of damaging your carpet or fabric upholstery.
  • works well on dirt and mud
  • dries very quickly
  • doesn't deter pets from re-soiling
Brand Simple Green
Model 432103
Weight 2.2 pounds
Rating 4.0 / 5.0

9. Nature's Miracle Urine Destroyer

Nature's Miracle Urine Destroyer uses an advanced bio-enzymatic formula that is enriched with oxygen to completely eliminate marks and smells of every kind. There are four size options, including a 1.5-gallon bottle with a battery-powered sprayer.
  • can be used inside litter boxes
  • ideal for dried messes
  • may damage wood surfaces
Brand Nature's Miracle
Model P-5727
Weight 2.7 pounds
Rating 5.0 / 5.0

8. Zero Odor

Zero Odor removes odors at a molecular level, so there is no chance of your pet picking up on a leftover scent and re-soiling the area. It breaks down stubborn stains thoroughly, causing them to disappear right before your eyes.
  • completely allergen-free
  • won't discolor carpets or upholstery
  • fragrance is a bit strong
Brand Zero Odor
Model ZOPSR 2023
Weight 1.2 pounds
Rating 3.5 / 5.0

7. Eco-88 Spray

Eco-88 Spray provides a reliable solution for tackling pet accidents, and you don't even have to rinse it out after application. It breaks down gas molecules until your couch or rug is as good as new, with no lingering foul smells.
  • removes coffee effectively
  • works on bedding and pillows
  • can cause skin irritation
Brand Eco-88
Model fes
Weight 2.3 pounds
Rating 4.7 / 5.0

6. Petzyme Cleaner

Petzyme Cleaner uses a blend of friendly bacteria, enzymes, citrus extracts, and plant-based surfactants to permanently remove those pesky stains and smells. The advanced formula works all by itself, without requiring deep scrubbing.
  • safe for use on mattresses
  • never tested on animals
  • cannot be used in a steam cleaner
Brand Petzyme
Model B00L4OTN68
Weight 2.3 pounds
Rating 4.4 / 5.0

5. Kids 'N' Pets Instant

Whether you need to remove a pet's urine and poop stains, or vomit spots from where a child accidentally spit up, Kids 'N' Pets Instant can get the job done. It is gentle enough to be used on any type of water-safe surface, including thick carpets and hardwood floors.
  • completely biodegradable formula
  • available in multi-packs
  • bottle is prone to leaking
Brand KIDS 'N' PETS
Model LEPUSHPDJ1134
Weight 4 pounds
Rating 4.0 / 5.0

4. Rocco & Roxie Eliminator

The Rocco & Roxie Eliminator is a best seller with its environmentally-friendly, bio-enzymatic formula that's guaranteed to make stains disappear — and quickly. It has even earned the prestigious seal of approval from the Carpet and Rug Institute, so you know it's good.
  • no leftover ammonia smell
  • safe for households with children
  • can be used to pre-treat laundry
Brand Rocco & Roxie Supply Co
Model fsec
Weight 2.3 pounds
Rating 4.5 / 5.0

3. Simple Solution

The affordable Simple Solution comes in 32-ounce and one-gallon sizes and works nearly as well as the most expensive stain removers on the market. It uses a combination of enzymes and pro-bacteria to naturally eat away smells and stains.
  • spray bottle with three settings
  • works on wine stains
  • money-back guarantee
Brand Simple Solution
Model 11051-3P
Weight 8.7 pounds
Rating 4.8 / 5.0

2. Angry Orange

Angry Orange was originally formulated for application in commercial settings, like boarding kennels, but it has since become available for residential use. It is a super-safe, nontoxic option derived from the oil of orange peels.
  • disinfects while removing stains
  • suitable for use outdoors
  • doesn't leave residue behind
Brand Angry Orange
Model pending
Weight 9.1 ounces
Rating 4.8 / 5.0

1. TriNova Advanced

The popular TriNova Advanced is a must-have for housebreaking pets, to prevent your carpets from being destroyed. Its all-natural, industrial-grade formula deeply cleans wood floors and upholstery without using harsh chemicals.
  • made in the united states
  • can remove stains from clothing
  • fragrance isn't overpowering
Brand TriNova
Model pending
Weight 2.2 pounds
Rating 5.0 / 5.0

Which Pet Stain Remover Is Best For Your Home?

The main active ingredients in a pet stain remover change dramatically depending on the brand, and whether the product is organic or made with more aggressive chemicals. People with small children in their home, or curious pets who will lick up any liquid on the ground, should stick to non-toxic stain removers, in case of accidental ingestion. Animal and environment lovers might want a formula that is environmentally friendly, so it doesn't send any harmful pollutants into the air.

In addition to protecting their kids and pets, people probably want to guard their furniture, too, which is why they should look for cleaners that state they are safe to use on wood and are chlorine-free. Some formulas treat the stain, but they don't eliminate the nasty odor left behind by vomit, urine, and feces. Pet stain removers with natural enzymatic bacteria break apart the particles that cause odor, leaving a room smelling like the accident never happened.

Removing odor isn't just about making a room smell tolerable for a person again; it also helps discourage animals from re-soiling the same area. There are several reasons dogs urine-mark a territory, and one of them is the fact that they smell another animal's pee there. So multi-pet households especially need to eliminate accident-related odors. Certain delicate fabrics cannot handle scrubbing, in which case one will need a pet stain remover that works on contact, with no extra scrubbing required. Some materials, like any microfiber fabric, shouldn't get wet. Households with microfiber furniture should look for a cleaning solution that doesn't require any rinsing.

How Bio-Enzymatic Cleaners Work

While some cleaners simply cover up odors, bio-enzymatic ones totally eliminate them. The particular combination of bacteria and microbial nutrients in these cleaners actually eats the organic waste produced by pets. Once these compounds digest the waste, they turn it into water and carbon dioxide (CO2), which are both odorless and colorless. After using a bio-enzymatic cleaner, all that should be left is CO2 and water, and since both of these naturally occur in the atmosphere, this type of cleaner is very environmentally friendly.

The wonderful thing about the bacteria in these cleaners is that they grow and multiply until they've completely consumed whatever natural waste they're near. For this reason, some of them can work for up to 80 hours after being applied to a stain. They essentially do not stop working until their work is done, unlike chemical-based cleaners, that often need to be applied over and over again. Sometimes a few of these cleaning bacteria survive even after the mess is eliminated, so they hang around, ready to tackle any new spots.

There are six different types of enzymes, three of which are used in these types of cleaner. Amylases break apart starch molecules, proteases destroy and digest protein-based molecules such as blood, and lipases work on fat molecules like oil. Between these three enzymes, there is almost no stain that a bio-enzymatic cleaner cannot remove, nor odor it cannot eliminate.

How To Stop Urine-Marking In The House

Since having one's carpet professionally cleaned can cost as much as $350, training a dog not to urine-mark in the home isn't only good dog parenting, it's also financially responsible. First off, unspayed and unneutered dogs urine-mark more than those who have been fixed. Trying any of these other training tactics will be especially hard on an unfixed dog.

Dogs tend to mark areas where they feel they haven't made their presence known. So, if a person catches their dog marking a certain room, they should actually spend more time with their dog in there, playing with them, feeding them and cuddling with them in there. This will make the dog feel that they don't need to mark the area. Many dog owners have had the experience of bringing a new item home, only to have their dog immediately pee on it. Dogs often mark things that are new and foreign to the home. Anything that a dog might view as foreign, like a guest's sweater, or a new painting, should be put somewhere that the dog cannot reach it.

Pet owners should take special precautions when introducing a new dog to the pack. Not doing so can result in fighting, and it can also result in excessive urine-marking. There is always the possibility that a dog is marking out of anxiety. Some mark compulsively when they're nervous, the way humans might bite their nails. If that is the case, the owner has to get to the root of the animal's anxiety.


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Last updated on May 26, 2018 by Taber Koeghan

Taber is a writer working in Los Angeles, which also happens to be the city she was raised in. She enjoys reading mysteries, rock climbing, and baking. A funny cat named Roswell lives in her house.


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