Updated January 17, 2019 by Quincy Miller

The 10 Best Enzyme Based Cleaners

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Best High-End
Best Mid-Range
Best Inexpensive

We spent 27 hours on research, videography, and editing, to review the top choices for this wiki. Keeping your home neat and tidy is extremely difficult, especially when you realize many household cleaners are filled with chemicals that you'd never willingly subject your family to. These enzyme-based options are capable of wiping away grime, pet stains, mold, and all manner of messes that may be lurking around your living areas — and they're safe for use near kids and animals. When users buy our independently chosen editorial picks, we may earn commissions to support our work. Skip to the best enzyme based cleaner on Amazon.

10. Earthworm Carpet & Upholstery

9. Bubba's Super Strength

8. Naturally It's Clean

7. Marigold & Peppa

6. Genesis Kleen-Free Naturally

5. Biokleen Bac-Out

4. Enzyme Magic

3. Aubrey & Alex

2. Puracy Natural

1. Nature's Miracle

Editor's Notes

January 16, 2019:

While some of the options on this list are targeted towards pet owners, their ability to break down and remove grass, urine, and poop stains means that they'll also do well on other common messes. However, we also included more general selections as well, so the immaculate homeowner might want to consider buying a few different brands to cover all their bases.


Quincy Miller
Last updated on January 17, 2019 by Quincy Miller

After getting his bachelor’s from the University of Texas, Quincy Miller moved out to Los Angeles, where he soon found work as a copywriter and researcher, specializing in health and wellness topics for a major online media brand. Quincy is also knowledgeable about home improvement, as he’s had extensive experience with everything from insulation to power tools to emergency room trips, sometimes in that order. Sharing a home with three dogs and a couple of cats has forced Quincy to learn as much as he can about pet supplies, animal nutrition and, most importantly, the best ways to tackle the mountains of fur that accumulate in every corner of your home.


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