The 10 Best Enzyme Drain Cleaners

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We spent 27 hours on research, videography, and editing, to review the top choices for this wiki. If panic typically sets in when you realize your pipes are backed up, relax. Although most household drain cleaners use toxic chemicals that are bad for your plumbing and the environment, these selections use natural enzymes to gently keep everything flowing smoothly without causing any damage. We've included options good for everything from toilets to garbage disposals to septic tanks. When users buy our independently chosen editorial picks, we may earn commissions to support our work. Skip to the best enzyme drain cleaner on Amazon.

10. Zep ZDC16

9. Natural Rapport Drain & Septic

8. Rid-X Treatment

7. FDC Break Down

6. Roebic Leach and Drain Field

5. Enzyme Magic Digester

4. Bio Clean

3. Black Diamond Stoneworks Get Serious

2. Green Gobbler Refresh

1. Helix Laboratories DrainScrub

Editor's Notes

May 09, 2019:

Drain cleaners that use enzymes to break down grease, oils, fat, hair, bath tissue, and other buildup have the environmental upper hand on their chemical-laden brethren. And while many are potent and will get the job done, the trade-off is that you may need to wait a bit longer for the magic to work. In many instances, prevention is the best method, and since these cleaners are safe for plumbing, septic systems, and the environment, they're ideal for monthly or weekly maintenance to keep clogs at bay.

For commercial applications, look to Black Diamond Stoneworks Get Serious and Helix Laboratories DrainScrub. Consider FDC Break Down for situations where a fast-acting solution is required. Zep ZDC16 is great if your building has ancient plumbing, while Green Gobbler is effective for garbage disposals and emits a zesty orange scent while it works. Bio Clean is another tried-and-true formula that uses a combination of enzymes and bacteria to eliminate organic matter. Each container is good for 100 uses and can be used in all manner of drains, from the kitchen to the bathroom, and even motorhomes and cat litter pans.

Nature's Soldiers was affected by availability concerns, so we supplanted it with Enzyme Magic Digester, which is much easier to administer, as it requires no preparation.


Gia Vescovi-Chiordi
Last updated on May 10, 2019 by Gia Vescovi-Chiordi

Born in Arizona, Gia is a writer and autodidact who fled the heat of the desert for California, where she enjoys drinking beer, overanalyzing the minutiae of life, and channeling Rick Steves. After arriving in Los Angeles a decade ago, she quickly nabbed a copywriting job at a major clothing company and derived years of editing and proofreading experience from her tenure there, all while sharpening her skills further with myriad freelance projects. In her spare time, she teaches herself French and Italian, has earned an ESL teaching certificate, traveled extensively throughout Europe and the United States, and unashamedly devours television shows and books. The result of these pursuits is expertise in fashion, travel, beauty, literature, textbooks, and pop culture, in addition to whatever obsession consumes her next.


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