Updated April 07, 2018 by Quincy Miller

The 10 Best Enzyme Drain Cleaners

video play icon
Best High-End
Best Mid-Range
Best Inexpensive

We spent 27 hours on research, videography, and editing, to review the top choices for this wiki. There are few feelings in the world as horrifying as the panic that sets in when you realize your pipes are backed up. Unfortunately, most household drain cleaners use toxic chemicals that are bad for your plumbing, not to mention the environment. These selections, on the other hand, use natural enzymes to gently keep everything flowing smoothly. When users buy our independently chosen editorial picks, we may earn commissions to support our work. Skip to the best enzyme drain cleaner on Amazon.

10. Nature's Soldiers

9. Zep ZDC16

8. Green Gobbler

7. Roebic Leach and Drain Field

6. FDC Break Down

5. Natural Rapport Drain & Septic

4. Black Diamond Stoneworks Get Serious

3. Helix Laboratories DrainScrub

2. Bio Clean

1. Rid-X Treatment

Quincy Miller
Last updated on April 07, 2018 by Quincy Miller

After getting his bachelor’s from the University of Texas, Quincy Miller moved out to Los Angeles, where he soon found work as a copywriter and researcher, specializing in health and wellness topics for a major online media brand. Quincy is also knowledgeable about home improvement, as he’s had extensive experience with everything from insulation to power tools to emergency room trips, sometimes in that order. Sharing a home with three dogs and a couple of cats has forced Quincy to learn as much as he can about pet supplies, animal nutrition and, most importantly, the best ways to tackle the mountains of fur that accumulate in every corner of your home.

Thanks for reading the fine print. About the Wiki: We don't accept sponsorships, free goods, samples, promotional products, or other benefits from any of the product brands featured on this page, except in cases where those brands are manufactured by the retailer to which we are linking. For our full ranking methodology, please read about us, linked below. The Wiki is a participant in associate programs from Amazon, Walmart, Ebay, Target, and others, and may earn advertising fees when you use our links to these websites. These fees will not increase your purchase price, which will be the same as any direct visitor to the merchant’s website. If you believe that your product should be included in this review, you may contact us, but we cannot guarantee a response, even if you send us flowers.